Publications

Lower Extremity: ​​

2025

• ​Longitudinal Recovery Following A Bone Anchored Prosthesis for Transfemoral Amputees: Prospective 12-month Follow-up Cohort Study

  • Jesse C. Christensen DPT, PhD, Bart Gillespie DPT, Erik K. Kubiak MD,  Jayant Agarwal MD, Sarina Sinclair PhD, 2025. CLICK HERE FOR LINK TO POSTER

2023

• ​Changes in frontal plane kinematics over 12-months in individuals with the Percutaneous Osseointegrated Prosthesis (POP)

  • Darter BJ, Syrett ED, Foreman KB, Kubiak E, Sinclair S. Changes in frontal plane kinematics over 12-months in individuals with the Percutaneous Osseointegrated Prosthesis (POP). PLoS One. 2023 Feb 22;18(2):e0281339. doi: 10.1371/journal.pone.0281339. PMID: 36812173; PMCID: PMC9946262.​

2022

• A preliminary, observational study using whole-blood RNA sequencing reveals differential expression of inflammatory and bone markers post-implantation of percutaneous osseointegrated prostheses

  • Miller A, Jeyapalina S, Agarwal J, Mansel M, Beck JP. A preliminary, observational study using whole-blood RNA sequencing reveals differential expression of inflammatory and bone markers post-implantation of percutaneous osseointegrated prostheses. PLoS One. 2022 May 26;17(5):e0268977. doi: 10.1371/journal.pone.0268977. PMID: 35617338; PMCID: PMC9135298.​

• ​The First FDA Approved Early Feasibility Study of a Novel Percutaneous Bone Anchored Prosthesis for Transfemoral Amputees: A Prospective 1-year Follow-up Cohort Study 

  • Sinclair S, Beck JP, Webster J, Agarwal J, Gillespie B, Stevens P, Gililland J, Kubiak E. The First FDA Approved Early Feasibility Study of a Novel Percutaneous Bone Anchored Prosthesis for Transfemoral Amputees: A Prospective 1-year Follow-up Cohort Study. Arch Phys Med Rehabil. 2022 Nov;103(11):2092-2104. doi: 10.1016/j.apmr.2022.06.008. Epub 2022 Jul 29. PMID: 35908658.​

2021

• ​Use of computer tomography imaging for analyzing bone remodeling around a percutaneous osseointegrated implant 

  • ​Wankier Z, Taylor C, Drew A, Kubiak E, Agarwal J, Sinclair S. Use of computer tomography imaging for analyzing bone remodeling around a percutaneous osseointegrated implant. J Orthop Res. 2022 Sep;40(9):2065-2075. doi: 10.1002/jor.25247. Epub 2021 Dec 27. PMID: 34910325.​

2019

• Analysis of the Stomal Microbiota of a Percutaneous Osseointegrated Prosthesis: A Longitudinal Prospective Cohort Study

  • ​Beck JP, Grogan M, Bennett BT, Jeyapalina S, Agarwal J, Bartow-McKenney C, Bugayev J, Kubiak E, Sinclair S, Grice E. Analysis of the Stomal Microbiota of a Percutaneous Osseointegrated Prosthesis: A Longitudinal Prospective Cohort Study. J Orthop Res. 2019 Dec;37(12):2645-2654. doi: 10.1002/jor.24421. Epub 2019 Aug 2. PMID: 31317568. 

 

Preclinical Research Studies

2014

• ​Radiographic evaluation of bone adaptation adjacent to percutaneous osseointegrated prostheses in a sheep model

  • Jeyapalina S, Beck JP, Bachus KN, Chalayon O, Bloebaum RD. Radiographic evaluation of bone adaptation adjacent to percutaneous osseointegrated prostheses in a sheep model. Clin Orthop Relat Res. 2014 Oct;472(10):2966-77. doi: 10.1007/s11999-014-3523-z. PMID: 24557934; PMCID: PMC4160482. ​

• Progression of bone ingrowth and attachment strength for stability of percutaneous osseointegrated prostheses

  • Jeyapalina S, Beck JP, Bloebaum RD, Bachus KN. Progression of bone ingrowth and attachment strength for stability of percutaneous osseointegrated prostheses. Clin Orthop Relat Res. 2014 Oct;472(10):2957-65. doi: 10.1007/s11999-013-3381-0. PMID: 24258685; PMCID: PMC4160472. ​

2012

• Efficacy of a porous-structured titanium subdermal barrier for preventing infection in percutaneous osseointegrated prostheses

  • Jeyapalina S, Beck JP, Bachus KN, Williams DL, Bloebaum RD. Efficacy of a porous-structured titanium subdermal barrier for preventing infection in percutaneous osseointegrated prostheses. J Orthop Res. 2012 Aug;30(8):1304-11. doi: 10.1002/jor.22081. Epub 2012 Jan 31. PMID: 22294380. ​

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Upper Extremity: 

2024

• Transhumeral prosthesis use affects upper body kinematics and kinetics.

  • ​Dunn JA, Gomez NG, Wong B, Sinclair SK, Henninger HB, Foreman KB, Bachus KN. Transhumeral prosthesis use affects upper body kinematics and kinetics. Gait Posture. 2024 Jul;112:59-66. doi: 10.1016/j.gaitpost.2024.05.007. Epub 2024 May 11. PMID: 38744022. 

• Extended physiological proprioception is affected by transhumeral Socket-Suspended prosthesis use.

  • ​Dunn JA, Wong B, Sinclair SK, Henninger HB, Bachus KN, Foreman KB. Extended physiological proprioception is affected by transhumeral Socket-Suspended prosthesis use. J Biomech. 2024 Mar;166:112054. doi: 10.1016/j.jbiomech.2024.112054. Epub 2024 Mar 20. PMID: 38513398.